Pepper Ann

Pamela Adlon

Moose (voice)

Kathleen Wilhoite

Pepper Ann (voice)

Danny Cooksey

Milo (voice)

Clea Lewis

Nicky (voice)

April Winchell

Mom (voice)

Jeff Bennett

Craig Bean / Dieter Liederhosen / Bob / Additional Voices (voices)

Kath Soucie

Cissy Rooney / Additional Voices (voice)

Candi Milo

Constance Goldman (voice)

Jenna Von Oÿ

Trinket St. Blair (voice)

Tino Insana

Uncle Jojo (voice)

Susan Tolsky

Aunt Janie (voice)

Cree Summer

Tessa and Vanessa James / Additional Voices (voice)

Alex Trebek

Paddi Edwards

Vera Groober-Schwartz (voice)

Don Lake

Mr. Sherman Finky (voice)

Don Adams

Principal Hickey (voice)

Jess Harnell

Additional Voices (voice)

Mark Hamill

Kathy Najimy

Coach Doogan (voice)

Tara Strong

Brenda / Female Scientist (voice)

Jim Cummings

Mr. Roland Carter (voice)

Kenn Michael

Lamar Abudabe (voice)

Maurice LaMarche

Chuck Pearson / Menorah / Colonel Delaney (voice)

Jodi Benson