Les Razmoket

E. G. Daily

Tommy Pickles (voice)

Kath Soucie

Phil DeVille / Lil DeVille (voice)

Cheryl Chase

Angelica Pickles (voice)

Melanie Chartoff

Didi Pickles (voice)

Jack Riley

Stu Pickles (voice)

Michael Bell

Drew Pickles / Chas Finster (voice)

Tress MacNeille

Charlotte Pickles (voice)

Cree Summer

Susie Carmichael (voice)

Christine Cavanaugh

Chuckie Finster (voice)

Joe Alaskey

Lou Pickles (voice)

David Doyle

Lou Pickles (voice)

Tara Strong

Dil Pickles (voice)

Dionne Quan

Kimi Finster (voice)

Nancy Cartwright

Chuckie Finster (voice)

Phil Proctor

Howard DeVille (voice)

Tony Jay

Dr. Lipschitz (voice)

Dana Hill

Little Kid (voice)

Scott Menville

Larry / Steve (voice)

Amanda Bynes

Taffy

Neil Ross

Scientist #1 / Radio Psychiatrist / Western Union Man (voice)

Danny Mann

Old Players #1 & #2 (voice)

Pamela Adlon

Dean (voice)

Jim Turner

Monster Voice (voice)

Gregg Berger

Metalitron / Marco (voice)